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Acute Symptoms: Chemical pneumonitis & non-cardiac pulmonary edema (after inhalation of metallic/elemental mercury) Severe gastroenteritis, shock, renal failure (mercury salt ingestion) Chronic Symptoms: Pink discoloration of the hands & feet & desquamation of the hands & feet (mercury vapor inhalation) Gingivitis (mercury vapor inhalation) Psychiatric disturbances ( , painful extremities, tunnel vision (mercury vapor inhalation) mad as a hatter ), irritability, tremors Nephrotoxicity, hemorrhagic gastroenteritis (inorganic mercury & ethylmercury) Perinatal exposure: mental retardation & a cerebral-palsy-type syndrome in offspring (methylmercury & possibly other forms of mercury) Treatment: Remove the source of mercury if possible ABCs Activated charcoal for GI decontamination Control diarrhea BAL - administer chelation therapy References: Olson KR (2007): Poisoning & Drug Overdose

Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice

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