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[DOI] [PMC free article] [PubMed] [Google Scholar] GeorgiouSiafis, S
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Electrophilic inhibitors of Keap1 have side effects due to off-target effects, and the resulting PPI inhibitors have been extensively studied and have broad clinical potential

This reaction pulls two electrons from G6P in order to reduce the coenzyme NADP+ to NADPH
