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By selectively blocking NNMT, 5-Amino-1MQ is investigated for its ability to preserve cellular NAD+ pools, reduce methylation of nicotinamide to inactive 1-methylnicotinamide (1-MNA), and enhance sirtuin activity and energy metabolism

[DOI] [PubMed] [Google Scholar] 51.Basso DM, Beattie MS, Bresnahan JC
