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References and where to read more For deeper reading, look for human randomized trials and metaanalyses that summarize weight and performance outcomes, and explore brand research pages that publish trial summaries and COAs
Isotretinoin has a variety of immunomodulatory effects
PubMed Central , Proceedings of the National Academy of Sciences of the United States of America , vol
Altered intestinal permeability (leaky gut) allows the passage of food antigens, toxins, bacteria, and microbial products, promoting inflammation and dysregulated immune responses, triggering autoimmunity through various mechanisms [188]
