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This hypomethylation suppresses MBP production, compromising myelin stability, similar PADI2 hypomethylation has been observed in PBMCs from MS patients (61)
Science 172:11431145 Messina S, Altavilla D, Aguennouz M, Seminara P, Minutoli L, Monici MC, Bitto A, Mazzeo A, Marini H, Squadrito F, Vita G (2006) Lipid peroxidation inhibition blunts nuclear factor-kappaB activation, reduces skeletal muscle degeneration, and enhances muscle function in mdx mice
Extracellular matrix molecules: potential targets in pharmacotherapy
They then separated the EXOs clusters with magnetic granules using a magnet
