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26 As the disease progresses, cells are no longer able to secrete enough insulin to compensate for the abnormally high blood glucose, leading to progression to prediabetes or T2D

Thus, mannose may serve as a promising therapeutic agent for the treatment of obesity, OP and associated conditions

From 1990 to 2019, the global number of deaths and disability-adjusted life years attributable to low bone mineral density (also called osteopenia) increased from 207,367 to 8.6 million to 437,884 and 16.6 million, respectively [5]

That framing is inaccurate and practically harmful
