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Thirdly, Macrophages secrete factors such as TGF-1, while CD8 + T cells release IFN, influencing cell ferroptosis

Recent studies suggest that combining NAMPT inhibitors with other therapies could enhance their efficacy and reduce resistance in cancer treatment, as shown in various preclinical animal models 217,218

Histone acetyltransferase (HAT) and histone deacetylase (HDAC) enzymes control the levels of histone acetylation, modulating gene expression (Cavalli and Heard, 2019)

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