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Redundancy among Wnt ligands is well established in numerous developing systems and mapping of gene expression show that most components of the pathway, including the Wnt ligands, are expressed in a strict spatio-temporal manner during chicken inner ear development (Sienknecht and Fekete, 2009

In particular, mossy fiber sprouting in hippocampal dentate granule cells lowers the seizure threshold and contributes to cognitive and emotional impairments (Hajszan and MacLusky, 2006)

Retrieved 16 April 2023
Mathiisen et al