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Neutrophil signaling disarray or enzymatic inhibition in Gsr / neutrophils during the phagocytosis may also explain why fewer yeast particles are engulfed and killed by Gsr / neutrophils than by WT cells (Fig

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Given that GSH has a molecular weight similar to that of amino acids, a plausible scenario is that when plants experience mechanical damage or insect attack, a large volume of GSH from the intracellular region may surge into the apoplastic region, inducing calcium influx by activation of the GLR3.3 ion channel