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Description
These findings demonstrate that STK38 specifically recognises the RHIM domains present in RIPK1 and RIPK3, suggesting a selective regulatory role within the necrosome complex rather than a broad interaction with all RHIM-containing scaffolds
For instance, through blocking the System Xc activity, erastin triggers ferroptosis, eventually inhibiting tumor growth in mouse models of lymphoma (114)
no subject in the trial surpassed the upper boundary of 110% of the prescribed number of prophylactic infusions
10.1016/j.ejphar.2020.173488 2 Al ZahraniN
