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When glutathione levels are depleted - as they consistently are in Hashimoto's thyroiditis, Graves' disease, and hypothyroidism - the consequences cascade: oxidative thyroid damage, protein modification, autoantigen formation, immune activation, and progressive thyroid destruction

doi:10.1186/1475-2859-12-87 Ayer A, Gourlay CW, Dawes IW (2013) Cellular redox homeostasis, reactive oxygen species and replicative ageing in Saccharomyces cerevisiae

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More researches are needed to put on the agenda to explore the function of elevated ROS and identify the exact ROS target pathways that will be most beneficial in treating gastric cancer