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During the analysis, the samples were kept in a 4C autosampler
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In the four-component Ugi reaction, the five different isocyanide derivatives of 4-hydroxythalidomide, in the presence of tritylamine or methylamine, formaldehyde, and acid-containing derivative of the target ligand (JQ1 derivative) yielded different anti-BRD4 PROTACs 178
doi: 10.1038/s41556-021-00708-8 8 NunesTBernardazziCde SouzaHS
