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Description
Endogenous (e.g., inflammation) and exogenous (e.g., diet components, toxicants, or drugs) factors can increase intestinal permeability and cause the formation of a so-called leaky gut. The latter is characterized by the penetration of food antigens, commensals, or pathogenic bacteria into the blood, causing the development of inflammation (Vanuytsel et al., 2021)

Prignano, F
To address this, the problem formulation (2) needs to be extended and transformed into an optimal control problem

Molecular sciences disorders of human coenzyme Q10 metabolism: an overview
