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The transparency of the crystalline lens decreases with age, leading to a gradual increase in absorbance within the blue light spectrum (Lee et al., 2016)

Therefore, it is not surprising that NAMPT is upregulated in these tumors, since cancer cells depend on its activity to satisfy their high NAD + demand

It has been shown that Nrf2 is related to mTOR and our data supported the notion that sulforaphane exerts neuronal protective effects via activating Nrf2 and mTOR

However, clinical recommendations from the European League Against Rheumatism (EULAR) and other organizations point to a multidisciplinary point of view of FM and its treatment (Giorgi et al., 2023