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Finally, because ALA aggressively improves cellular glucose uptake and insulin sensitivity, patients taking prescription metabolic medications (like Metformin or insulin) should monitor their blood sugar closely to help avoid hypoglycemia (low blood sugar)

We performed a randomized placebo-controlled trial of the mitochondrial enhancers acetyl-L-carnitine (ALCAR) and -lipoic acid (ALA) in patients with bipolar depression, and assessed markers of cerebral energy metabolism using phosphorus magnetic resonance spectroscopy
Propionyl-L-carnitine: This form helps increase levels of nitric oxide in the body, which dilates the blood vessels to promote better blood flow