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10.1371/journal.pmed.1000097 37 NIHR (2025)
Diarrhea: NAD+ supplements can cause diarrhea, especially if taken in high doses
Researchers utilize this complex blend to investigate the intersection of these pathways, specifically evaluating how simultaneously fueling the NAD+ salvage pathway and providing mitochondrial signaling peptides impacts metabolic flux, insulin resistance, and cellular longevity models
In another study, chronic administration of AOD9604 for 14 days reduced body weight and body fat in obese mice
