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It remains useful for estimating near-term probability, particularly in older adults where the short-term horizon and absolute risk align more closely

* Correspondence: Xinshu Li, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

National Health and Medical Research Council (2010) Guidelines for the screening, prognosis, diagnosis, management and prevention of glaucoma

The dose-response curve between 8 and 12 mg shows diminishing returns, meaning 10 mg captures most of the benefit while potentially reducing some of the dose-related side effects seen at 12 mg