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In human postmortem brains [Brodmann area (BA) 8, frontal cortex] (1 st sample set) (Appendix Table S7), RTqPCR analyses revealed increased expressions of MPST and CBS in subjects with schizophrenia (Fig 6A and B), with no change in CTH mRNA levels (Fig 6C)
[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Brooks A.J., Waters M.J
This creates a conformational change in the receptor, causing activation of a G protein
At the chemical level, molecular degradation, misfolding, or post-translational modifications can convert these molecules into pro-inflammatory ones
