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Apoptotic caspases suppress type I interferon production via the cleavage of cGAS, MAVS, and IRF3

The ligand preferably is a ligand for a glutathione transporter of a vertebrate target cell, more preferably a glutathione transporter of a mammalian target cell, and most preferably a glutathione transporter of a human target cell

In addition to sustaining hypoxic and ischemic conditions, rapidly decreasing oxygen up to 0.1%, the ACU can also rapidly re-oxygenate the measurement chamber of the CLARIOstar Plus to simulate reperfusion

An NMR metabolomics strategy was applied, with a view to assess the short-term (up to 48 h) metabolic dynamics of each untreated cell line, aiming at identifying metabolic traits characterizing cDDP-acquired resistance in TNBC