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Dermatological hyperpigmentation extends beyond intended tanning areas in approximately 1218% of subjects, particularly affecting pre-existing nevi (moles), freckles, and areas of post-inflammatory hyperpigmentation

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Interestingly, analysis of the datasets from Oncomine cancer microarray database confirmed a lower PLC expression in the lung adenocarcinoma tissues as compared to the respective normal tissues suggesting rather tumor suppressor role of this protein for lung tumor development [26](Figure 2B)