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[2] [3] Coenzyme A (CoA) plays a key role in the Krebs cycle in mitochondria, which is essential for the production of ATP, which powers many reactions in cells

Inhibition of mitochondrial (etomoxir) and peroxisomal (thioridazine) fatty acid oxidation revealed that each organelle contributes to approximately half of acetyl-CoA produced from palmitate in the DKO cells (Supplemental Figure 5G)

Furthermore, cytokines are small proteins that play an important role in cell signaling and immune function