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Clinical decision-making and treatment of myelodysplastic syndromes

have demonstrated that APP-related mutations produce an epigenetic shift in an AD model cell line in addition to a general decrease in DNA methylation in the hippocampus of postmortem AD patients (Sung et al., 2011

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Research has demonstrated that baicalein suppresses the NF-B signaling pathway in MPTP-induced PD mice models, which lowers the production of pro-inflammatory cytokines and, in turn, decreases astrocyte activation (Lee et al., 2014)