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Moreover, in this type of diabetes, the mitochondria are smaller, rounder and more likely to produce superoxide

Luo et al., 2023)] may trigger a systemic-central inflammatory cascade via the gut-brain axis (Lim, 2018) The overproduction of ROS by microglia is hypothesized to be a pivotal mediator in this process, inducing an increase in NLRP3 inflammasome-mediated IL-1 elevation within the POA (Zhang Z

Graphs correspond to BRET measurements in HEK293T cells co-expressing a BRET-based biosensor for free G and the indicated amounts of mem-GsBP2 were stimulated with the indicated concentrations of isoproterenol