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Description
Except for the possible lack of sophistication in subject selection, the detection tools adopted and the potential mechanisms explored remain largely within the standard paradigm

This article organizes the reported mechanisms around that coordination-chemistry starting point, moving from the metal-binding site outward to cellular and transcriptional observations

18 This triple therapy combines one potentiator (ivacaftor) with two correctors (elexacaftor and tezacaftor) to increase CFTR protein quantity and function

Bieging KT, Fish K, Bondada S, Longnecker R
