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Conversely, the M2 phenotype supports tissue repair and synaptic remodeling following the pro-inflammatory phase through the secretion of anti-inflammatory cytokines [i.e., IL-10 and transforming growth factor-beta (TGF-)]

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Banting lecture 1988

There is accumulating evidence that coating might reduce eryptosis-inducing properties of nanomaterials [450, 452, 457], which can be exploited to engineer NPs with a better hemocompatibility profile
