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This study was carried out in accordance with the recommendations of the respective Institutional Review Boards (IRBs), described below with written informed consent from parents of subjects and assent where appropriate

NeuroImage: Clinical 12, 4756

It is predicted that the negatively charged carboxylate ion in the -alanine zwitterion can act as a ligand to bind to the positively charged Cu 2+ , Zn 2+ , and/or Fe 2+ ions, facilitating chelation and preventing the catalytic conversion of O2 into ROS, thereby reducing neuronal damage

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