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Interaction with Growth Factors and Angiogenesis One of the most often examined mechanisms pertains to angiogenesis, the development of new blood vessels
Potential concerns include effects on angiogenesis that theoretically could influence tumor development or progression, though preclinical studies show context-dependent effects that inhibit pathological angiogenesis in some tumor models

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reviews connect NNMT overexpression to obesity, insulin resistance, fatty-liver progression, and other conditions [2,8,9]
