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Description
It also restricts the blood supply to the skin, affecting nutrition and oxygen supply
Self-Assembling Protein Microarrays
The N-terminal 13-amino-acid extension and the E3R substitution in LR3 reduce binding affinity to IGFBPs by approximately one to two orders of magnitude, increasing the free IGF-1 fraction available to bind the type 1 IGF receptor at any given total concentration
Acknowledgements The authors thank the members of the Levy and Thaiss labs for valuable discussions and input
