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demonstrated that while the sensitivity of detecting highly acidic oligosaccharides in positive ion mode using DHB was slightly reduced, it did significantly minimize the loss of sulfate residues, thereby enhancing the reliability of the analysis
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Thus, it is extremely difficult or even impossible to determine if the lesion had originally been associated with a nevus or not, they write
Clearly, some of these atypical proliferations can metastasize and relatively infrequently cause death (111,128,129)
