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Nystrom E, Bengtsson C, Lapidus L, Petersen K, Lindstedt G

In this regard, the product of NO reaction with O 2 leads to the formation of ONOO , which is a strong oxidant that reacts with lipids, DNA, and proteins via direct oxidative reactions or via indirect, radical-mediated mechanisms [36]

However, neuropsychiatric symptoms developing on the basis of direct brain tissue pathology or underlying vascular dysfunction are considered to be a major and the most common feature of long COVID [4, 7, 31, 37, 65, 88, 113], with potentially devastating consequences for affected individuals

DKK1 were significantly lower in the KO group in both the mRNA and protein levels