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Because kaempferol regulates metabolic and reproductive pathways, SERC administration also restored the LH/FSH ratio, improved insulin sensitivity, and balanced hormone levels

We hypothesized that the emergence of metabolic syndrome in individuals with schizophrenia occurs even before the initiation of antipsychotic treatment, potentially due to oxidative stress abnormalities, which may in turn be influenced by polymorphisms in the glutathione-regulating gene GCLC

( Epub 2019 Jul 3 )

Different bile acids and chenodeoxycholic acids act as natural ligand for FXR, whose expression is elevated in the liver and intestine