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The most commonly used salt-forming counterions in FDA-approved drugs are hydrochloride, sodium salt, and toluene sulfonate salts 68 , 69

Bolt P, Clerk AN, Luu HH, et al

Downregulation of PERK activity and eIF2 serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells

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