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Signs of Vitamin B12 Deficiency Some common signs that you may be deficient in Vitamin B12 include fatigue or tiredness, weakness, difficulty concentrating or thinking clearly, pale skin, dizziness or light-headedness, loss of appetite, weight loss, constipation or diarrhea, numbness or tingling in the hands and feet, sore tongue, headaches and vision problems

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Monitor for metabolic disturbances and reproductive changes: track fasting glucose, HbA1c, lipid panels, menstrual patterns, and pregnancy tests if conception is possible