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Description
Abstract Background Administration of valproic acid (VPA) is complicated with approximately 0.9% of patients developing hyperammonemia, but the pathogenesis of this adverse effect remains to be clarified

In rare instances, it could potentially aggravate hypothyroidism or heighten the risk of seizures, particularly in those with a history of these conditions
doi:10.1161/01.ATV.0000146266.65820.a1 182
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