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Description
More recently, spinocerebellar ataxia type 2 has also been linked to the presence of a transition polymorphism in the GSTO2 gene (rs2297235 A183G) which significantly correlates with the age at disease onset

CD8 + T cells, activated by APCs via MHC class I molecules, differentiate into cytotoxic T lymphocytes (CTLs), which eliminate pathogen-infected or tumor cells through the release of perforin and granzymes [34, 35]

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Sun et al., 2009
