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Description
Confirming the significant role of Met35 of A1742 in these observations, when the Met35 residue was substituted by norleucine (as noted above, CH 2 in place of the S-atom of Met), no oxidative damage or neurotoxicity to hippocampal neurons was found (115)
Polar metabolites were separated using a Vanquish U-HPLC system (Thermo Fisher Scientific) coupled to a Q-Exactive HF-X mass spectrometer equipped with an HESI probe (Thermo Fisher Scientific), operating in negative ion mode
Gaynes BN
The same counts when the occupancy of Cu 2+ involves less than 6 ions
