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Description
As these cytokines have been reported to reduce cell viability and proliferation in LNCaP cells, reducing these cytokines may be one reason for the decrease in cytotoxicity
Reducing oil production and sebaceous gland shrinkage: Accutane drastically reduces sebum (oil) production and shrinks the sebaceous glands, especially in oily areas like the T-zone (forehead, nose, and chin)

However, its precise mechanisms and broader biological effects require further study, particularly in human clinical trials
Clemente-Postigo M, Munoz-Garach A, Serrano M, et al