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With developments in novel skin permeation enhancing methods such as microneedles and laser, copper compounds can potentially be used on skin for cosmeceutical or medicinal purposes 5,11,12
Limited time-course evaluations in low and medium confidence studies suggest that tissue injury can persist for a period of at least 4 weeks in rats, although these outcomes subsided by week 14

[DOI] [PMC free article] [PubMed] [Google Scholar] 395.Karmakar S, Banik NL, and Ray SK

However, it may also be administered slowly by intravenous or subcutaneous injection
