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Surrounding blood vessels deliver oxygen and nutrients required for rapid cell division, while follicle cells produce the keratin proteins that form the hair shaft

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First described as a neurotoxin in rodents in the 1960s, cuprizone reliably produces toxic effects including demyelination, hydrocephalus, and astrogliosis.[1,2] The cuprizone mouse captures some aspects of multiple sclerosis (MS), providing a model of demyelination and spontaneous remyelination