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doi: 10.1021/acs.jpcb.0c09296 116 Marn-HernndezAGracia-MoraIRuiz-RamrezLMoreno-SnchezR
GHS-R suppression presents a promising strategy for obesity control through multiple cellular and molecular mechanisms, and GHS-R antagonists may serve as unique and powerful drugs for combating obesity, inflammation and insulin resistance
Many oncogenes and tumor suppressor genes have been shown to be important for cellular metabolism pathways (Boroughs And DeBerardinis 2015), involving aerobic glycolysis (metabolic conversion of glucose into lactate even in the presence of oxygen), glutaminolysis (degradation of glutamine to gain cellular energy), and one-carbon metabolism (interlinking metabolic pathways that include the methionine and folate cycles) (Clare et al
