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This cycle is supported by glutathione reductase, which recycles the oxidized glutathione back to its active form using energy from NADPH

Yang and co-workers reported a nanomedicine composed of dendritic mesoporous silica nanoparticles (DMSNs), Fe 3 O 4 , Mn, and glutaminase inhibitor Telaglenastat (CB-839) (termed DFMC) for restored oxaliplatin chemosensitivity on the basis of the GSH-responsive and -exhausting effect (Figure 4C) (Figure 4D)

T2DM, also referred to as non-insulin-dependent DM, is a multifactorial endocrine-metabolic disorder characterized by hyperglycemia and dyslipidemia

miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549