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This includes people with pernicious anemia, a condition where the body lacks intrinsic factors, making it impossible to absorb B12 from food
In addition, it has been demonstrated that these anti-CD38 mAbs also have a potential in vivo immune modulatory effects on the tumor microenvironment such as enhancing effector T-cell function and inhibiting suppressive T-reg activity (42)
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The -emitter astatine-211 targeted to CD38 can eradicate multiple myeloma in a disseminated disease model
