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However, there are at least two independent steps in the NFKB activation cascade: kinase pathways and redox-signaling pathway
oIGF-1 at a concentration of 10 ng mL 1 in DMEM increased myoblast proliferation by 22% compared to DMEM alone ( p = 0.045 by post hoc analysis) (Figure 2)

Butcher EC, Berg EL, Kunkel EJ (2004) Systems biology in drug discovery

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