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Seek urgent medical attention (call 999 or attend A&E) if you experience: Severe abdominal pain, particularly if accompanied by vomiting Signs of pancreatitis: severe upper abdominal pain radiating to the back Symptoms of severe dehydration: confusion, rapid heartbeat, very low urine output Allergic reactions: difficulty breathing, facial swelling, severe rash Your healthcare provider may wish to investigate potential underlying causes of fatigue through blood tests , including: Full blood count (to check for anaemia) Thyroid function tests Vitamin B12 and folate levels Iron studies Kidney and liver function HbA1c (if diabetic or pre-diabetic) In some cases, dose adjustment or temporary treatment interruption may be necessary to allow recovery from side effects

Springer Protocols Handbooks

Despite the need for further enhancement and assessment of its pharmacokinetics and safety profile, GPS emerges as a promising lead metabolite for novel drug development