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Binding at a threefold excess molar concentration of zinc revealed the second binding site of the metal at His50 in the N terminus but no additional affinity was noted for the C terminus

The other view: The trace element selenium as a micronutrient in thyroid disease, diabetes, and beyond
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Finally, no changes were observed in relative mRNA levels of SOD1 and SOD2 in conventional MASH patients (Nagaya et al