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For example, blood concentrations of the three metabolites of trichloroethylenechloral hydrate, trichloroethanol, and trichloroacetic acid over time after administration of an oral dose of trichloroethylene at 1,000 mg/kg to male Osborne-Mendel rats and male B6C3F 1 mice were markedly higher in mice than in rats, whereas concentrations for trichloroethylene were higher in rats than in mice, indicating more rapid metabolism and elimination of trichloroethylene (Prout et al

[DOI] [PubMed] [Google Scholar] 230.Perovic D., Kolenc D., Bilic V., Somun N., Drmic D., Elabjer E., Buljat G., Seiwerth S., Sikiric P

doi: 10.1016/j.bmc.2020.115821

Researchers established the VICD rat model by performing permanent bilateral carotid artery blockage surgery to evaluate iron and oxidative stress indicators (Li et al., 2012)