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217,218 A recent analysis of human blood samples does confirm that, with age, most hypermethylation is not related to changes in cell composition, but directly related to ageing

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used TCGA, The University of Alabama at Birmingham Cancer (UALCAN), KaplanMeier plotter, The Breast cancer Gene-Expression Miner v4.7 (bc-GenExMiner v4.7), cBioPortal, STRING, Enrichr, MethSurv, and Tumor IMmune Estimation Resource (TIMER) for bioinformatics analysis, to find that high levels of CCL 4/5/14/19/21/22 were associated with better overall survival (OS) and recurrence-free survival (RFS), while elevated expression of CCL 24 was associated with shorter OS in BC patients

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