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This reduces material waste, supports procedural efficiency, and lowers the risk of accidental microbial introduction during repeated laboratory manipulation
Additional observed toxic mechanisms included loss of MMP, upregulation of the proapoptotic protein Bcl-2-associated X protein (BAX), and downregulation of antiapoptotic markers such as B-cell lymphoma 2 (Bcl-2), poly ADP ribose polymerase (PARP), and caspase-3 [134]
10.2147/DDDT.S83144 Drug Des Devel Ther
