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L-glutamate condenses with L-cysteine to form -L-glutamyl-L-cysteine, which requires GCS in presence of ATP, K + and Mg ++ with the formation of the enzyme bound -glutamyl-(P) as an intermediate.[9] -carboxyl group of glutamate form a peptide -linkage after reaction with the amino group of cysteine, which protects glutathione from hydrolysis by intracellular peptidase

J Clin Endocrinol Metab 98(2):769776 Marino M, Rotondo Dottore G, Ionni I et al (2019) Serum antibodies against the insulin-like growth factor-1 receptor (IGF-1R) in Graves disease and Graves orbitopathy

Airway and Circulating Levels of Carotenoids in Asthma and Healthy Controls