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GbE, a traditional Chinese herbal medicine, has a long history of medical use for treating cerebral dysfunction, brain aging, and neurodegenerative dementia (Abdou et al

doi: 10.3389/fphar.2019.01360 Received 01 August 2019 Accepted 28 October 2019 Published 19 November 2019 Volume 10 - 2019 Edited by Amedeo Amedei, University of Florence, Italy Reviewed by Brian J

In addition, mitochondria also play an important role in influencing intracellular calcium levels, reactive oxygen species (ROS) production, regulating innate immune responses, and apoptosis ( Androgens can regulate glucose and lipid metabolism by affecting mitochondrial density, quality, and function

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